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Abstract

Annual mugwort (Artemisia annua) is commonly found in Asia. Besides its antimalarial effect, Artemisia annua might have some roles in arthritis due to its bioactive components. Objective: The paper aims to describe the possible role of annual mugwort (Artemisia annua) in treating arthritis. Methods: This paper is a narrative literature review. Literature was chosen from PubMed, Science Direct, and Google Scholar. Selected journals were published within 10 years. Results: Artemisia annua is well known in Asia, Europe, Australia, and America. The sesquiterpene lactone artemisinin compound in this medicinal plant is related to the antimalarial effect. The main components are flavonoids, phenolic acids, sesquiterpene lactones, and coumarins. It is often used in the treatment for dysentery, malaria, jaundice, tuberculosis, hemorrhoids, and autoimmune disease. Recently, it was found that Artemisia annua has some unique properties such as antioxidant, analgesic, and anti-inflammatory. Based on these properties, Artemisia annua is developed as a natural remedy for osteoarthritis. Artemisia annua leaves also diminish the concentration of proinflammatory cytokines, interleukin-6, and interleukin-8. Conclusion: In conclusion, the possible role of Artemisia annua in arthritis might be related to its analgesic and anti-inflammatory properties. Further studies are needed to explore the possible dosage, contraindication, and side effects.


 

Keywords

Annual mugwort, Artemisia annua, Arthritis, Osteoarthritis

Article Details

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