Main Article Content
Abstract
Pain is one of the most prevalent symptoms experienced by cancer patients and often becomes a common complaint post-treatment. Analgesics are necessary to treat pain. Analgesics are medications utilized to reduce or eliminate pain without inducing loss of consciousness. However, the specific analgesics used may vary depending on the severity of the pain. Therefore, the objective of this research is to provide a more detailed overview of the utilization of analgesics and other co administered medications in cancer patients undergoing chemotherapy. This study is an observational research. Data were obtained retrospectively using the medical records of cancer patients undergoing chemotherapy at Palembang Hospital from January to December 2020, employing purposive sampling method, and subsequently analyzed descriptively. The sample consisted of 45 medical record data. Therapeutic data for cancer patients included the observation of the use of single or combination cytostatic drugs, such as doxorubicin and docetaxel, the combination of docetaxel and carboplatin, as well as other adjunct medications described descriptively. From the 45 collected medical records of cancer patients, the results indicate that analgesics were not administered to cancer patients. Instead, non-pharmacological therapy, specifically deep breathing relaxation techniques, was employed by the patients. The combination of cytostatic drugs, doxorubicin, and docetaxel, was used in 23 patients (82.14%) for breast cancer patients, and a combination of docetaxel and carboplatin was utilized in 7 patients (41.18%) for lung cancer patients. Other adjunct medications included anti-inflammatory (dexamethasone), antiemetic (ondansetron), antacid (omeprazole), antihistamine (diphenhydramine), and vitamins. The administration of the anti- inflammatory dexamethasone has replaced the use of analgesics, which were not given at all to cancer patients undergoing chemotherapy.
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References
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- Andarmoyo, S. (2013). Konsep & ProsesKeperawatan Nyeri. Ar-Ruzz Media.
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- Ferlay J, Ervik M, Lam F, Colombet M, Mery L, Piñeros M, Znaor A, Soerjomataram I, B. F. (2020).
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References
Ambarwati, W. N., & Wardani, E. K. (2014). Efek Samping Kemoterapi Secara Fisik Pasien Penderita Kanker Servik. Jurnal.Unimus.Ac.Id, 97–106.
American Cancer Society. (2021). Lung Cancer Risk Factors.
Andarmoyo, S. (2013). Konsep & ProsesKeperawatan Nyeri. Ar-Ruzz Media.
Anderson, W. F., Althuis, M. D., Brinton, L. A., & Devesa,S. S. (2004). Is male breast cancer similar or different than female breast cancer? Breast Cancer Research and Treatment, 83(1), 77–86.
Bray, F., Ferlay, J., Soerjomataram, I., Siegel, R. L., Torre, L. A., & Jemal, A. (2018). Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: A Cancer Journal for Clinicians, 68(6), 394–424.
Britton, T. M. B., & Purushotham, A. D. (2009). Understanding breast cancer- related lymphoedema. Surgeon, 7(2), 120–124.
Care, S., & Series, B. (2016). Nausea and. Farastuti, D., & Windiastuti, E. (2005).Penanganan Nyeri pada Keganasan. Sari Pediatri, 7(3), 153.
Deng G. Integrative Medicine Therapies for Pain Management in Cancer Patients. Cancer J. 2019 Sep/Oct;25(5):343-348.
Ferlay J, Ervik M, Lam F, Colombet M, Mery L, Piñeros M, Znaor A, Soerjomataram I, B. F. (2020).
International Agency for Research on Cancer 2020. Global Cancer Observatory: Cancer Today., 419, 1–2.
Fink RM, Gallagher E. Cancer Pain Assessment and Measurement. Semin Oncol Nurs. 2019 Jun;35(3):229- 234.
Gardian, L., & Eddy, H. (2007). Tata Laksana Farmakologis Nyeri Kanker. In Tata Laksana Farmakologis Nyeri Kanker (pp. 121–123)
Gärtner, R., Jensen, M.-B., Nielsen, J., Ewertz, M., Kroman, N., & Kehlet, H. (2010). Prevalence of and Factors Associated With Persistent Pain Following Breast Cancer Surgery. Journal American Medical Association, 302(18), e1985– e1992.
Herawati, F., & Pratiwi, V. F. (2018). Penggunaan Analgesik untuk Perawatan Paliatif Pasien Kanker di Poli Paliatif Puskesmas di Kota Surabaya. MPI (Media Pharmaceutica Indonesiana), 2(1), 13–21.
Higashi, T., Yoshimoto, T., & Matoba, M. (2012). Prevalence of analgesic prescriptions among patients with cancer in Japan: an analysis of health insurance claims data. Global Journal of Health Science, 4(6), 197–203.
Kay Conerly and Harriet Lebowitz. Editors 2022, Current Medical Diagnosis & Treatment 2022, Sixty- first Edition Copyright © 2022 by McGraw Hill. All rights reserved.
Kementerian Kesehatan Republik Indonesia. (2019). Panduan Penatalaksanaan Kanker Payudara (Breast Cancer Treatment Guideline). Jurnal Kesehatan Masyarakat, 4(4), 1–50
Kementerian Kesehatan RI. (2015) Kanker. In Infodatin Pusat Data dan Informasi Kementerian Kesehatan RI.
Kementerian Kesehatan RI. (2019). Hari Kanker Sedunia 2019.
Komite Penanggulangan Kanker Nasional. (2015). Panduan penatalaksanaan kankerprostat.
Kementerian Kesehatan Republik Indonesia, 1–47. Pinzon, R. T. (2016). Pengkajian nyeri komprehensif.
Mattiuzzi C, Lippi G. Current Cancer Epidemiology. J Epidemiol Glob Health. 2019 Dec;9(4):217- 222.
Miller M, Hanna N. Advances in systemic therapy for non- small cell lung cancer. BMJ. 2021 Nov
;375:n2363.
Pusat Informasi Obat Nasional. (2015). No Title. http://pionas.pom.go.id/ioni/bab-8- keganasan-danimunosupresi/81-keganasan/815- antineoplastik- lain/taksan
Rahardja, T. H. T. & K. (2015). Obat-Obat Penting, Khasiat, Penggunaan, dan Efek- Efek Sampingnya (Ketujuh). PT Elex Media Komputindo Kelompok Gramedia.
Rahmah, D. S. (2009). Evaluasi Penggunaan Obat Antimuntah pada Pasien Retinoblastoma Anak yang Menjalani Kemoterapi di Rumah Sakit Kanker “Dharmais.” Indonesian Journal of Cancer, 3(1), 1–4.
Rolf-Detlef Treede. (2018). The International Association for the Study of Pain definition of pain: as valid in 2018 as in 1979, but in need of regularly updated footnotes. Pain Reports, 3, e643.
Shumway, D. A., Sabolch, A., & Jagsi, R. (2020). Breast Cancer. Medical Radiology, 1–43.
Suwondo, B. S., Meliala, L., & Sudadi. (2017). Buku Ajar Nyeri 2017.
Swarm RA, Paice JA, Anghelescu DL, Are M, Bruce JY, Buga S, Chwistek M, Cleeland C, Craig D, Gafford E, Greenlee H, Hansen E, Kamal AH, Kamdar MM, LeGrand S, Mackey S, McDowell MR, Moryl N, Nabell LM, Nesbit S; BCPS; O'Connor N, Rabow MW, Rickerson E, Shatsky R, Sindt J, Urba SG, Youngwerth JM, Hammond LJ, Gurski LA. Adult Cancer Pain, Version 3.2019, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2019 Aug 1;17(8):977-1007
Tjahya, A. (2017). Penilaian nyeri. Academia, 133–163. Tyson, J. F. K. & L. B. (2018). 100 Tanya Jawab mengenai Gejala Kanker dan Efek Samping Pengobatan Kanker (Edisi Kedu). PT Indeks.
Utami, W. (2013). Chemotherapy Induced Nausea Vomitting. 10(02), 159–170.
World Health Organization.(2018).Cancer. https://www.who.int/health- topics/cancer#tab=tab_1
World Health Organization. (2020). Cancer Incident in Indonesia. International Agency for Research on Cancer, 858, 1– 2.
Zhang F, Shen A, Jin Y, Qiang W. The management strategies of cancer- associated anorexia: a critical appraisal of systematic reviews. BMC Complement Altern Med. 2018 Aug 9;18(1):236.
World Health Organization. Global Health Estimates 2016: dis ease burden by cause, age, sex, by country and by region, 2000– 2016.Geneva: World Health Organization; 2018.